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R-422D (MO29) is a reliable, non-ozone-depleting refrigerant engineered as a direct replacement for R-22 in existing air conditioning and refrigeration systems. It delivers dependable cooling performance while allowing for a smooth and cost-effective retrofit process.
Designed to work with mineral, alkylbenzene (AB), and POE oils, R-422D eliminates the need for an oil change in most R-22 systems. This significantly reduces downtime, labor costs, and system modification requirements — making it an ideal solution for HVAC contractors and facility managers upgrading legacy equipment.
R-422D helps extend the life of existing systems while meeting modern environmental standards, offering a practical and compliant alternative to phased-out R-22.
R-422D, commonly known as MO29, is a non-ozone-depleting HFC blend engineered as a direct replacement for R-22 in air conditioning and refrigeration systems. It delivers dependable cooling performance with minimal system modifications.
- ASHRAE Classification: A1 (Non-flammable, Low toxicity)
- Zero Ozone Depletion Potential (ODP)
- Designed for R-22 Retrofits
- Compatible with Mineral, AB, and POE Oils
- Stable Performance in Medium-Temperature Applications
- Direct Expansion (DX) chillers
- High-pressure heat pumps
- Residential and light commercial air conditioning systems
- Commercial packaged HVAC units
When purchasing from Refrigerants Depot, you can be confident that all refrigerants are brand new, 100% virgin products. Every cylinder meets or exceeds ARI-700 purity standards to ensure safety, consistency, and reliable system performance.
Most orders ship within 1 business day, ensuring fast and reliable delivery for professional HVAC applications.




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